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Cellosaurus NCI-H2731 (CVCL_U995)

[Text version]

Cell line name NCI-H2731
Synonyms H2731; H-2731; NCIH2731
Accession CVCL_U995
Resource Identification Initiative To cite this cell line use: NCI-H2731 (RRID:CVCL_U995)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Array-based CGH.
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: Transcriptome analysis.
Genome ancestry Source: PubMed=30894373

Origin% genome
African0
Native American0.84
East Asian, North1.33
East Asian, South0
South Asian1.88
European, North65.41
European, South30.53
Disease Pleural sarcomatoid mesothelioma (NCIt: C45663)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; PubMed=25877200

Markers:
AmelogeninX
CSF1PO10
D3S135817
D5S81811,12
D7S8208,14
D8S11798,12
D13S31711,13 (Cosmic-CLP)
11 (PubMed=25877200)
D16S53913
D18S5115
D21S1130,31.2
FGA21
Penta D11,12
Penta E12
TH016,9.3
TPOX8,11
vWA18

Run an STR similarity search on this cell line
Publications

PubMed=11030152; DOI=10.1038/sj.onc.1203815
Modi S., Kubo A., Oie H., Coxon A.B., Rehmatulla A., Kaye F.J.
Protein expression of the RB-related gene family and SV40 large T antigen in mesothelioma and lung cancer.
Oncogene 19:4632-4639(2000)

PubMed=23830731; DOI=10.1016/j.cancergen.2013.04.006
Klorin G., Rozenblum E., Glebov O.K., Walker R.L., Park Y., Meltzer P.S., Kirsch I.R., Kaye F.J., Roschke A.V.
Integrated high-resolution array CGH and SKY analysis of homozygous deletions and other genomic alterations present in malignant mesothelioma cell lines.
Cancer Genet. 206:191-205(2013)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

Cross-references
Cell line databases/resources CCLE; NCIH2731_PLEURA
Cell_Model_Passport; SIDM00098
Cosmic-CLP; 1240134
DepMap; ACH-002129
GDSC; 1240134
Biological sample resources BioSample; SAMN03471019
Chemistry resources PharmacoDB; H2731_426_2019
Gene expression databases ArrayExpress; E-MTAB-3610
GEO; GSM1669824
Other Wikidata; Q54908000
Entry history
Entry creation16-Apr-2014
Last entry updated06-Sep-2019
Version number17