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Cellosaurus OVPA8 (CVCL_UC75)

[Text version]
Cell line name OVPA8
Synonyms OVPA-8
Accession CVCL_UC75
Resource Identification Initiative To cite this cell line use: OVPA8 (RRID:CVCL_UC75)
Comments Population: Caucasian.
Doubling time: ~44 hours (PubMed=30018258); 50-60 hours (DSMZ=ACC-871); 40-44 hours (ECACC=19062601).
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations
  • Gene deletion; HGNC; 1101; BRCA2; Zygosity=Heterozygous (PubMed=30018258).
  • Mutation; HGNC; 1100; BRCA1; Simple; p.Val1234Glnfs*8 (c.3695_3699GTAAA[1]) (c.3700_3704delGTAAA) (3819del5) (3819_3823delGTAAA); ClinVar=VCV000037542; Zygosity=Homozygous (PubMed=30018258).
  • Mutation; HGNC; 11998; TP53; Simple; p.Gly245Ser (c.733G>A); ClinVar=VCV000012365; Zygosity=Homozygous (PubMed=30018258).
Disease High grade ovarian serous adenocarcinoma (NCIt: C105555)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 47Y
Category Cancer cell line
STR profile Source(s): DSMZ; ECACC; PubMed=30018258

Markers:
AmelogeninX
CSF1PO10,11
D1S165615
D2S44114
D2S133821,25
D3S135815
D5S8189,13
D7S8208,9
D8S117911,14 (DSMZ; PubMed=30018258)
14 (ECACC)
D10S124814,15
D12S39121
D13S31711
D16S53912,14
D18S5112
D19S43313,15
D21S1129,30
D22S104515
FGA22,25
Penta D13
Penta E5
TH018
TPOX9,11
vWA14

Run an STR similarity search on this cell line
Web pages https://www.phe-culturecollections.org.uk/media/174720/ovpa8_cell_line_profile8_final.pdf
Publications

PubMed=30018258; DOI=10.3390/ijms19072080
Tudrej P., Olbryt M., Zembala-Nozynska E., Kujawa K.A., Cortez A.J., Fiszer-Kierzkowska A., Piglowski W., Nikiel B., Glowala-Kosinska M., Bartkowska-Chrobok A., Smagur A., Fidyk W., Lisowska K.M.
Establishment and characterization of the novel high-grade serous ovarian cancer cell line OVPA8.
Int. J. Mol. Sci. 19:2080.1-2080.26(2018)

Cross-references
Cell line collections (Providers) DSMZ; ACC-871
ECACC; 19062601
Cell line databases/resources cancercelllines; CVCL_UC75
DSMZCellDive; ACC-871
Encyclopedic resources Wikidata; Q98128408
Entry history
Entry creation13-Nov-2018
Last entry update05-Oct-2023
Version number10