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Cellosaurus DIF2 (CVCL_UF10)

[Text version]

Cell line name DIF2
Accession CVCL_UF10
Resource Identification Initiative To cite this cell line use: DIF2 (RRID:CVCL_UF10)
Comments Characteristics: Moderately resistant to both the antiviral and antiproliferative actions of interferons.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Sequence variations Homozygous for B2M p.Met1Ile (c.3G>C) (from parent cell line).
Homozygous for CTNNB1 p.Ala5_Ala80del (c.14_241del228) (from parent cell line).
TP53 p.Arg213Ter (c.637C>T) (from parent cell line).
Disease Epstein-Barr virus-related Burkitt lymphoma (NCIt: C27694)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0008 (Daudi)
Sex of cell Male
Age at sampling 16Y
Category Cancer cell line
Publications

PubMed=6319552; DOI=10.1099/0022-1317-64-12-2649
Tovey M.G., Dron M., Mogensen K.E., Lebleu B., Mechti N., Begonlours-Guymarho J.
Isolation of Daudi cells with reduced sensitivity to interferon. II On the mechanisms of resistance.
J. Gen. Virol. 64:2649-2653(1983)

PubMed=6420510; DOI=10.1099/0022-1317-64-12-2641
Dron M., Tovey M.G.
Isolation of Daudi cells with reduced sensitivity to interferon. I Characterization.
J. Gen. Virol. 64:2641-2647(1983)

Entry history
Entry creation13-Nov-2018
Last entry updated24-May-2019
Version number2