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Cellosaurus DIF9 (CVCL_UF15)

[Text version]

Cell line name DIF9
Accession CVCL_UF15
Resource Identification Initiative To cite this cell line use: DIF9 (RRID:CVCL_UF15)
Comments Characteristics: Resistant to both the antiviral and antiproliferative actions of interferons.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Sequence variations Homozygous for B2M p.Met1Ile (c.3G>C) (from parent cell line).
Homozygous for CTNNB1 p.Ala5_Ala80del (c.14_241del228) (from parent cell line).
TP53 p.Arg213Ter (c.637C>T) (from parent cell line).
Disease Epstein-Barr virus-related Burkitt lymphoma (NCIt: C27694)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0008 (Daudi)
Sex of cell Male
Age at sampling 16Y
Category Cancer cell line

PubMed=2580049; DOI=10.1099/0022-1317-66-4-787
Dron M., Tovey M.G., Eid P.
Isolation of Daudi cells with reduced sensitivity to interferon. III Interferon-induced proteins in relation to the phenotype of interferon resistance.
J. Gen. Virol. 66:787-795(1985)

PubMed=2937878; DOI=10.1099/0022-1317-67-4-663
Dron M., Tovey M.G., Uze G.
Isolation of Daudi cells with reduced sensitivity to interferon. IV Characterization of clones with altered binding of human interferon alpha subspecies.
J. Gen. Virol. 67:663-669(1986)

Entry history
Entry creation13-Nov-2018
Last entry updated24-May-2019
Version number2