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Cellosaurus DIF9 (CVCL_UF15)

[Text version]

Cell line name DIF9
Accession CVCL_UF15
Resource Identification Initiative To cite this cell line use: DIF9 (RRID:CVCL_UF15)
Comments Population: African; Kenyan.
Characteristics: Resistant to both the antiviral and antiproliferative actions of interferons.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Sequence variations MYC-IGH gene fusion (from parent cell line).
Homozygous for B2M p.Met1Ile (c.3G>C) (from parent cell line).
Homozygous for CTNNB1 p.Ala5_Ala80del (c.14_241del228) (from parent cell line).
Heterozygous for TP53 p.Gly266Glu (c.797G>A) (ClinVar=VCV000161516) (from parent cell line).
Disease EBV-related Burkitt lymphoma (NCIt: C27694)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0008 (Daudi)
Sex of cell Male
Age at sampling 16Y
Category Cancer cell line

PubMed=2580049; DOI=10.1099/0022-1317-66-4-787
Dron M., Tovey M.G., Eid P.
Isolation of Daudi cells with reduced sensitivity to interferon. III Interferon-induced proteins in relation to the phenotype of interferon resistance.
J. Gen. Virol. 66:787-795(1985)

PubMed=2937878; DOI=10.1099/0022-1317-67-4-663
Dron M., Tovey M.G., Uze G.
Isolation of Daudi cells with reduced sensitivity to interferon. IV Characterization of clones with altered binding of human interferon alpha subspecies.
J. Gen. Virol. 67:663-669(1986)

Other Wikidata; Q93527528
Entry history
Entry creation13-Nov-2018
Last entry updated02-Jul-2020
Version number4