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Cellosaurus HEK-Blue IL-18 (CVCL_UF33)

[Text version]

Cell line name HEK-Blue IL-18
Accession CVCL_UF33
Resource Identification Initiative To cite this cell line use: HEK-Blue IL-18 (RRID:CVCL_UF33)
Comments Characteristics: Designed to detect bioactive IL18 by monitoring the activation of the NF-kB and AP-1 pathways. In addition, the TNF-alpha and the IL-1beta responses have been blocked (InvivoGen).
Characteristics: SEAP (secreted ALPP) reporter cell line, in this cell line SEAP is under the control of a promoter with NF-kappaB and AP-1-binding sites.
Knockout cell: Method=Not specified; HGNC; 5993; IL1R1.
Knockout cell: Method=Not specified; HGNC; 5995; IL1RAP.
Knockout cell: Method=Not specified; HGNC; 11916; TNFRSF1A.
Knockout cell: Method=Not specified; HGNC; 11917; TNFRSF1B.
Transfected with: HGNC; 439; ALPP.
Transfected with: HGNC; 5988; IL18R1.
Transfected with: HGNC; 5989; IL18RAP.
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0045 (HEK293)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Web pages https://www.invivogen.com/hek-blue-il18
Cross-references
Other Wikidata; Q94092308
Entry history
Entry creation13-Nov-2018
Last entry update02-Jul-2020
Version number2