ID   HEK-Blue IL-18
AC   CVCL_UF33
DR   Wikidata; Q94092308
WW   https://www.invivogen.com/hek-blue-il18
CC   Characteristics: Designed to detect bioactive human IL18 (and to a lesser extent mouse IL18) by monitoring the activation of the NF-kappaB and AP-1 pathways. In addition, the TNF-alpha and the IL-1beta responses have been blocked (InvivoGen).
CC   Characteristics: SEAP (secreted ALPP) reporter cell line, in this cell line SEAP is under the control of a promoter with NF-kappaB and AP-1-binding sites.
CC   Knockout cell: Method=Not specified; HGNC; 5993; IL1R1.
CC   Knockout cell: Method=Not specified; HGNC; 5995; IL1RAP.
CC   Knockout cell: Method=Not specified; HGNC; 11916; TNFRSF1A.
CC   Knockout cell: Method=Not specified; HGNC; 11917; TNFRSF1B.
CC   Transfected with: HGNC; 439; ALPP.
CC   Transfected with: HGNC; 5988; IL18R1.
CC   Transfected with: HGNC; 5989; IL18RAP.
CC   Transfected with: UniProtKB; P33967; B.cereus Bsr.
CC   Transfected with: UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Transfected with: UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR).
CC   Transformant: NCBI_TaxID; 28285; Adenovirus 5.
CC   Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0045 ! HEK293
SX   Female
AG   Fetus
CA   Transformed cell line
DT   Created: 13-11-18; Last updated: 05-10-23; Version: 8
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