ID   HEK293 CYP2D6*10
AC   CVCL_UH09
SY   CYP2D6*10 (P34S/S486T) Expressing HEK293 Cell Line
DR   Wikidata; Q94093000
RX   PubMed=28603633;
CC   Transfected with: HGNC; 2625; CYP2D6 (with p.Pro34Ser and p.Ser486Thr).
CC   Transformant: NCBI_TaxID; 28285; Adenovirus 5.
CC   Miscellaneous: Cell line has been lost. Attempt to re-clone it are underway.
CC   Derived from sampling site: Fetal kidney.
OX   NCBI_TaxID=9606; ! Homo sapiens
HI   CVCL_0045 ! HEK293
SX   Female
AG   Fetus
CA   Transformed cell line
DT   Created: 13-11-18; Last updated: 29-10-20; Version: 4
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RX   PubMed=28603633; DOI=10.1002/prp2.314;
RA   Peterson A., Xia Z., Chen G., Lazarus P.;
RT   "In vitro metabolism of exemestane by hepatic cytochrome P450s: impact
RT   of nonsynonymous polymorphisms on formation of the active metabolite
RT   17beta-dihydroexemestane.";
RL   Pharmacol. Res. Perspect. 5:E00314-E00314(2017).
//