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Cellosaurus HEK293 CYP2D6*17-V5 (CVCL_UH10)

[Text version]

Cell line name HEK293 CYP2D6*17-V5
Synonyms CYP2D6*17 (T107I/R296C/S486T - V5 tag) Expressing HEK293 Cell Line
Accession CVCL_UH10
Resource Identification Initiative To cite this cell line use: HEK293 CYP2D6*17-V5 (RRID:CVCL_UH10)
Comments Characteristics: Expresses CYP2D6*17 with a C-terminal V5 tag.
Transfected with: HGNC; 2625; CYP2D6 (with p.Thr107Ile, p.Arg296Cys and p.Ser486Thr).
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0045 (HEK293)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line

PubMed=28603633; DOI=10.1002/prp2.314
Peterson A., Xia Z., Chen G., Lazarus P.
In vitro metabolism of exemestane by hepatic cytochrome P450s: impact of nonsynonymous polymorphisms on formation of the active metabolite 17beta-dihydroexemestane.
Pharmacol. Res. Perspect. 5:E00314-E00314(2017)

Cell line collections Kerafast; EWU033
Other Wikidata; Q94093005
Entry history
Entry creation13-Nov-2018
Last entry update02-Jul-2020
Version number2