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Cellosaurus SU/SR (CVCL_UI51)

[Text version]
Cell line name SU/SR
Accession CVCL_UI51
Resource Identification Initiative To cite this cell line use: SU/SR (RRID:CVCL_UI51)
Comments Population: Japanese.
Selected for resistance to: ChEBI; CHEBI:45783; Imatinib (Gleevec; STI571).
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Sequence variations
  • Gene fusion; HGNC; 76; ABL1 + HGNC; 1014; BCR; Name(s)=BCR-ABL1, BCR-ABL (PubMed=18783828).
  • Mutation; HGNC; 76; ABL1; Simple; p.Thr315Ile (c.944C>T) (c.1001C>T); ClinVar=VCV000012624; Zygosity=Unspecified (PubMed=18783828).
Disease Adult B acute lymphoblastic leukemia with t(9;22)(q34.1;q11.2) BCR-ABL1 (NCIt: C114819)
B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2) (ORDO: Orphanet_585909)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_UI50 (SU-Ph2)
Sex of cell Female
Age at sampling 50Y
Category Cancer cell line
Publications

PubMed=18783828; DOI=10.1016/j.leukres.2008.07.023
Hirase C., Maeda Y., Takai S., Kanamaru A.
Hypersensitivity of Ph-positive lymphoid cell lines to rapamycin: possible clinical application of mTOR inhibitor.
Leuk. Res. 33:450-459(2009)

Cross-references
Cell line databases/resources cancercelllines; CVCL_UI51
Encyclopedic resources Wikidata; Q98132865
Entry history
Entry creation25-Feb-2019
Last entry update05-Oct-2023
Version number10