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Cellosaurus POT1b F/- (#12436-2) (CVCL_UJ00)

Cell line name POT1b F/- (#12436-2)
Accession CVCL_UJ00
Resource Identification Initiative To cite this cell line use: POT1b F/- (#12436-2) (RRID:CVCL_UJ00)
Comments Characteristics: Embryonic fibroblasts that have loxP sites on both sides of the 3rd coding exon of one allele of mouse Pot1b. The second allele is deleted. Pot1b knockout can be effected by transduction of Cre recombinase into the cell line.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: 129P2/Ola x C57BL/6J.
Sex of cell Sex unspecified
Age at sampling 13-14FD
Category Transformed cell line
Publications

PubMed=16839877; DOI=10.1016/j.cell.2006.04.044
Hockemeyer D., Daniels J.-P., Takai H., de Lange T.
Recent expansion of the telomeric complex in rodents: two distinct POT1 proteins protect mouse telomeres.
Cell 126:63-77(2006)

Cross-references
Cell line collections (Providers) ATCC; CRL-3322
Encyclopedic resources Wikidata; Q98128657
Entry history
Entry creation25-Feb-2019
Last entry update21-Mar-2023
Version number3