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Cellosaurus Brca1 delta11/delta11 53Bp1-/- MEF (S7) (CVCL_UJ18)

[Text version]
Cell line name Brca1 delta11/delta11 53Bp1-/- MEF (S7)
Synonyms Brac1 delta11/delta1153Bp1-/- (S7)
Accession CVCL_UJ18
Resource Identification Initiative To cite this cell line use: Brca1 delta11/delta11 53Bp1-/- MEF (S7) (RRID:CVCL_UJ18)
Comments Characteristics: Established from mice homologous for Brca1 Ex11del.
Knockout cell: Method=KO mouse; MGI; MGI:1351320; Trp53bp1.
Derived from site: In situ; Embryo; UBERON=UBERON_0000922.
Cell type: Fibroblast; CL=CL_0000057.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Sex of cell Sex unspecified
Age at sampling 12-13FD
Category Finite cell line
Publications

PubMed=20362325; DOI=10.1016/j.cell.2010.03.012
Bunting S.F., Callen E., Wong N., Chen H.-T., Polato F., Gunn A., Bothmer A., Feldhahn N., Fernandez-Capetillo O., Cao L., Xu X.-L., Deng C.-X., Finkel T., Nussenzweig M.C., Stark J.M., Nussenzweig A.
53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks.
Cell 141:243-254(2010)

Cross-references
Cell line collections (Providers) ATCC; CRL-3264
Encyclopedic resources Wikidata; Q93431460
Entry history
Entry creation25-Feb-2019
Last entry update29-Jun-2023
Version number6