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Cellosaurus RCC4/empty vector (CVCL_UY81)

[Text version]

Cell line name RCC4/empty vector
Synonyms RCC4 plus vector alone
Accession CVCL_UY81
Resource Identification Initiative To cite this cell line use: RCC4/empty vector (RRID:CVCL_UY81)
Comments Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Sequence variations Hemizygous for VHL p.Ser65Trp (c.194C>G) (from parent cell line).
Disease Clear cell renal cell carcinoma (NCIt: C4033)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0498 (RCC4)
Category Cancer cell line
STR profile Source(s): ECACC

Markers:
AmelogeninX
CSF1PO10,12
D5S81812
D7S8208.2
D13S31712
D16S53911
TH019.3
TPOX11
vWA16

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Publications

PubMed=10353251; DOI=10.1038/20459
Maxwell P.H., Wiesener M.S., Chang G.-W., Clifford S.C., Vaux E.C., Cockman M.E., Wykoff C.C., Pugh C.W., Maher E.R., Ratcliffe P.J.
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis.
Nature 399:271-275(1999)

Cross-references
Cell line collections ECACC; 03112702
Entry history
Entry creation25-Feb-2019
Last entry updated25-Feb-2019
Version number1