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Cellosaurus BE(2)-C/CHCg (CVCL_V010)

[Text version]

Cell line name BE(2)-C/CHCg
Accession CVCL_V010
Resource Identification Initiative To cite this cell line use: BE(2)-C/CHCg (RRID:CVCL_V010)
Comments Population: Caucasian.
Characteristics: Intermediate type (I-type) (from parent cell line).
Characteristics: MYCN-amplified NBL cell line (from parent cell line).
Selected for resistance to: ChEBI; CHEBI:23359; Colchicine.
Sequence variations
  • Gene deletion; HGNC; 11998; TP53; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Cys135Phe (c.404G>T); ClinVar=VCV000376559; Zygosity=Heterozygous (from parent cell line).
Disease Neuroblastoma (NCIt: C3270)
Neuroblastoma (ORDO: Orphanet_635)
Derived from metastatic site: Bone marrow.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0529 (SK-N-BE(2)-C)
Sex of cell Male
Age at sampling 2Y2M
Category Cancer cell line
Publications

PubMed=8660514; DOI=10.1006/abio.1996.0176
Levchenko A., Mehta B.M., Spengler B.A., Narkar A.A., Fonti R., Biedler J.L., Tsuruo T., Larson S.M.
Measurement of P-glycoprotein expression in multidrug-resistant human neuroblastoma cell lines using self-competitive binding assay.
Anal. Biochem. 236:338-343(1996)

Cross-references
Encyclopedic resources Wikidata; Q54795870
Entry history
Entry creation16-Apr-2014
Last entry update23-Jun-2022
Version number14