ID   AND-1 MLLAF4 FLT3 D835
AC   CVCL_V163
SY   AND1-MLLAF4 FLT3 D835; AND1-MLLAF4/FLT3-TKD
DR   ISCR; 2206
DR   Wikidata; Q54749922
RX   PubMed=23479570;
WW   https://www.isciii.es/QueHacemos/Servicios/BIOBANCOS/BNLC/Lists/Lneas%20embrionarias/Attachments/36/Caracteristicas%20-%20Dossier-AND1-FLT3-D835.pdf
CC   Part of: Spanish Stem Cell Bank (Banco Nacional de Lineas Celulares) collection.
CC   From: Centre for Genomics and Oncological Research (GENYO); Granada; Spain.
CC   Characteristics: Transduced with both a pRRL-EF1a-MLLAF4-PGK-Neo and a pRRL-EF1a-FLT3 D835-PGK-GFP constructs.
CC   Karyotypic information: 46,XY,+i(7)p(11),-7 (BNLC).
CC   Transfected with: HGNC; 7135; AFF1 (KMT2-AFF1/MLL-AF4 fusion).
CC   Transfected with: HGNC; 7132; KMT2A (KMT2-AFF1/MLL-AF4 fusion).
CC   Transfected with: HGNC; 3765; FLT3 (with p.Asp835Xaa).
CC   Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP).
CC   Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
CC   Cell type: Embryonic stem cell; CL=CL_0002322.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_B526 ! AND-1
SX   Male
AG   Blastocyst stage
CA   Embryonic stem cell
DT   Created: 16-04-14; Last updated: 30-01-24; Version: 10
//
RX   PubMed=23479570; DOI=10.1182/blood-2012-11-470146;
RA   Bueno C., Ayllon V., Montes R., Navarro-Montero O., Ramos-Mejia V.,
RA   Real P.J., Romero-Moya D., Arauzo-Bravo M.J., Menendez P.;
RT   "FLT3 activation cooperates with MLL-AF4 fusion protein to abrogate
RT   the hematopoietic specification of human ESCs.";
RL   Blood 121:3867-3878(2013).
//