ID   MCF7 Tet-On
AC   CVCL_V332
SY   MCF7 Tet On; MCF-7 Tet-On
DR   Wikidata; Q54904453
CC   Characteristics: Transfected with reverse tetracycline-controlled transactivator (rtTA), a fusion between a mutated version of E.coli TetR and the activating domain of HSV-1 VP16.
CC   Sequence variation: Homozygous for CDKN2A deletion (from parent cell line).
CC   Sequence variation: Heterozygous for PIK3CA p.Glu545Lys (c.1633G>A) (ClinVar=VCV000013655) (from parent cell line).
CC   Transfected with: UniProtKB; P04483; E.coli Tn10 tetR.
CC   Transfected with: UniProtKB; P06492; Human herpesvirus 1 VP16 (UL28) (with del 1-360).
CC   Discontinued: Clontech; Catalog number 630918.
CC   Derived from metastatic site: Pleural effusion.
DI   NCIt; C4194; Invasive ductal carcinoma, not otherwise specified
OX   NCBI_TaxID=9606; ! Homo sapiens
HI   CVCL_0031 ! MCF-7
SX   Female
AG   69Y
CA   Cancer cell line
DT   Created: 16-04-14; Last updated: 02-07-20; Version: 9