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Cellosaurus T-47D Tet-On (CVCL_V334)

[Text version]
Cell line name T-47D Tet-On
Accession CVCL_V334
Resource Identification Initiative To cite this cell line use: T-47D Tet-On (RRID:CVCL_V334)
Comments Population: Caucasian.
Characteristics: Transfected with reverse tetracycline-controlled transactivator (rtTA), a fusion between a mutated version of E.coli TetR and the activating domain of HSV-1 VP16.
Transfected with: UniProtKB; P04483; Escherichia coli Tn10 tetR.
Transfected with: UniProtKB; P06492; Human herpesvirus 1 VP16 (UL28) (with p.Met1_Arg360del).
Discontinued: Takara/Clontech; Catalog number 630923.
Discontinued: Takara/Clontech; Catalog number 631144.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Mutation; HGNC; 8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Leu194Phe (c.580C>T); ClinVar=VCV000127817; Zygosity=Homozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0553 (T-47D)
Sex of cell Female
Age at sampling 54Y
Category Cancer cell line
Cross-references
Cell line databases/resources cancercelllines; CVCL_V334
Encyclopedic resources Wikidata; Q54971346
Entry history
Entry creation16-Apr-2014
Last entry update30-Jan-2024
Version number16