Cellosaurus logo
expasy logo

Cellosaurus U2-OS-Luc Tet-On (CVCL_V336)

[Text version]
Cell line name U2-OS-Luc Tet-On
Synonyms U-2 OS-Luc teT-on; U2OSLUC Tet ON
Accession CVCL_V336
Resource Identification Initiative To cite this cell line use: U2-OS-Luc Tet-On (RRID:CVCL_V336)
Comments Population: Caucasian.
Characteristics: Transfected with reverse tetracycline-controlled transactivator (rtTA), a fusion between a mutated version of E.coli TetR and the activating domain of HSV-1 VP16.
Characteristics: The firefly luciferase reporter gene is under the control of a tetracycline-responsive promoter.
Transfected with: UniProtKB; P04483; Escherichia coli Tn10 tetR.
Transfected with: UniProtKB; P06492; Human herpesvirus 1 VP16 (UL28) (with p.Met1_Arg360del).
Transfected with: UniProtKB; P08659; Firefly luciferase.
Derived from site: In situ; Bone, tibia; UBERON=UBERON_0000979.
Sequence variations
  • Mutation; HGNC; 9277; PPM1D; Simple; p.Arg458Ter (c.1372C>T); ClinVar=VCV002445214; Zygosity=Heterozygous (from parent cell line).
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0042 (U2OS)
Sex of cell Female
Age at sampling 15Y
Category Cancer cell line
STR profile Source(s): CCRID

Markers:
AmelogeninX
CSF1PO12,13
D2S133820,24
D3S135816
D5S8188,11
D7S82011,12
D8S117912,14
D13S31713
D16S53911,12
D18S5112,14
D19S43315
D21S1131
FGA20
TH016,9.3
TPOX11,12
vWA14,18

Run an STR similarity search on this cell line
Web pages http://www.clontech.com/xxclt_ibcGetAttachment.jsp?cItemId=26874
Cross-references
Cell line databases/resources CCRID; 1101HUM-PUMC000270
Encyclopedic resources Wikidata; Q54973629
Entry history
Entry creation16-Apr-2014
Last entry update05-Oct-2023
Version number16