ID   U2-OS-Luc Tet-On
AC   CVCL_V336
SY   U-2 OS-Luc teT-on; U2OSLUC Tet ON
DR   CCRID; 1101HUM-PUMC000270
DR   Wikidata; Q54973629
WW   http://www.clontech.com/xxclt_ibcGetAttachment.jsp?cItemId=26874
CC   Population: Caucasian.
CC   Characteristics: Transfected with reverse tetracycline-controlled transactivator (rtTA), a fusion between a mutated version of E.coli TetR and the activating domain of HSV-1 VP16.
CC   Characteristics: The firefly luciferase reporter gene is under the control of a tetracycline-responsive promoter.
CC   Sequence variation: Mutation; HGNC; 9277; PPM1D; Simple; p.Arg458Ter (c.1372C>T); ClinVar=VCV002445214; Zygosity=Heterozygous (from parent cell line).
CC   Transfected with: UniProtKB; P04483; Escherichia coli Tn10 tetR.
CC   Transfected with: UniProtKB; P06492; Human herpesvirus 1 VP16 (UL28) (with p.Met1_Arg360del).
CC   Transfected with: UniProtKB; P08659; Firefly luciferase.
CC   Derived from site: In situ; Bone, tibia; UBERON=UBERON_0000979.
ST   Source(s): CCRID
ST   Amelogenin: X
ST   CSF1PO: 12,13
ST   D13S317: 13
ST   D16S539: 11,12
ST   D18S51: 12,14
ST   D19S433: 15
ST   D21S11: 31
ST   D2S1338: 20,24
ST   D3S1358: 16
ST   D5S818: 8,11
ST   D7S820: 11,12
ST   D8S1179: 12,14
ST   FGA: 20
ST   TH01: 6,9.3
ST   TPOX: 11,12
ST   vWA: 14,18
DI   NCIt; C9145; Osteosarcoma
DI   ORDO; Orphanet_668; Osteosarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0042 ! U2OS
SX   Female
AG   15Y
CA   Cancer cell line
DT   Created: 16-04-14; Last updated: 05-10-23; Version: 16
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