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Cellosaurus PC-9/ZD (CVCL_V337)

[Text version]

Cell line name PC-9/ZD
Synonyms PC9 ZD
Accession CVCL_V337
Resource Identification Initiative To cite this cell line use: PC-9/ZD (RRID:CVCL_V337)
Comments Selected for resistance to: ChEBI; CHEBI:49668; Gefitinib (ZD1839; Iressa).
Omics: Transcriptome analysis.
Sequence variations EGFR p.Glu746_Ala750del (c.2235_2249del15) (from parent cell line).
Homozygous for TP53 p.Arg248Gln (c.743G>A) (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Derived from metastatic site: Lymph node.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_B260 (PC-9)
Sex of cell Male
Age at sampling 45Y
Category Cancer cell line
Publications

PubMed=15761868; DOI=10.1002/ijc.20985
Koizumi F., Shimoyama T., Taguchi F., Saijo N., Nishio K.
Establishment of a human non-small cell lung cancer cell line resistant to gefitinib.
Int. J. Cancer 116:36-44(2005)

Cross-references
Gene expression databases GEO; GSM1374824
Other Wikidata; Q54938509
Polymorphism and mutation databases Cosmic; 911754
Entry history
Entry creation16-Apr-2014
Last entry updated06-Sep-2019
Version number10