ID   PC-9/ZD
AC   CVCL_V337
SY   PC9 ZD
DR   cancercelllines; CVCL_V337
DR   Cosmic; 911754
DR   GEO; GSM1374824
DR   Wikidata; Q54938509
RX   PubMed=15761868;
CC   Population: Japanese.
CC   Selected for resistance to: ChEBI; CHEBI:49668; Gefitinib (ZD1839; Iressa).
CC   Sequence variation: Mutation; HGNC; 3236; EGFR; Simple; p.Glu746_Ala750del (c.2235_2249del15); ClinVar=VCV000163343; Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Homozygous (from parent cell line).
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000027.
DI   NCIt; C3512; Lung adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_B260 ! PC-9
SX   Male
AG   45Y
CA   Cancer cell line
DT   Created: 16-04-14; Last updated: 05-10-23; Version: 17
//
RX   PubMed=15761868; DOI=10.1002/ijc.20985;
RA   Koizumi F., Shimoyama T., Taguchi F., Saijo N., Nishio K.;
RT   "Establishment of a human non-small cell lung cancer cell line
RT   resistant to gefitinib.";
RL   Int. J. Cancer 116:36-44(2005).
//