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Cellosaurus HT-1080 Tet-Off (CVCL_V355)

Cell line name HT-1080 Tet-Off
Synonyms Tet-off HT-1080
Accession CVCL_V355
Resource Identification Initiative To cite this cell line use: HT-1080 Tet-Off (RRID:CVCL_V355)
Comments Characteristics: Transfected with the tetracycline transactivator (tTA) protein, a fusion of tetR with the activation domain of HSV-1 VP16.
Transfected with: UniProtKB; P04483; E.coli Tn10 tetR.
Transfected with: UniProtKB; P04486; Human herpesvirus 1 VP16 (UL28) (with del 1-360).
Sequence variations Heterozygous for IDH1 p.Arg132Cys (c.394C>T) (from parent cell line).
Disease Fibrosarcoma (NCIt: C3043)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0317 (HT-1080)
Sex of cell Male
Age at sampling 35Y
Category Cancer cell line
Web pages http://www.clontech.com/US/Products/Inducible_Systems/Tetracycline-Inducible_Expression/ibcGetAttachment.jsp?cItemId=26892
Cell line databases/resources TOKU-E; 3749
Other Wikidata; Q54896500