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Cellosaurus SUP-M2-CR03 (CVCL_V405)

[Text version]

Cell line name SUP-M2-CR03
Synonyms SUPM2CR03
Accession CVCL_V405
Resource Identification Initiative To cite this cell line use: SUP-M2-CR03 (RRID:CVCL_V405)
Comments Selected for resistance to: ChEBI; CHEBI:64310; Crizotinib (Xalkori).
Derived from sampling site: Cerebrospinal fluid.
Sequence variations Gene fusion; HGNC; 427; ALK + HGNC; 7910; NPM1; Name(s)=NPM1-ALK (from parent cell line).
Disease Anaplastic large cell lymphoma, ALK-positive (NCIt: C37193)
ALK-positive anaplastic large cell lymphoma (ORDO: Orphanet_300895)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2209 (SUP-M2)
Sex of cell Female
Age at sampling 5Y
Category Cancer cell line

PubMed=23239810; DOI=10.1158/1541-7786.MCR-12-0569
Ceccon M., Mologni L., Bisson W., Scapozza L., Gambacorti-Passerini C.
Crizotinib-resistant NPM-ALK mutants confer differential sensitivity to unrelated Alk inhibitors.
Mol. Cancer Res. 11:122-132(2013)

Encyclopedic resources Wikidata; Q54970878
Polymorphism and mutation databases Cosmic; 1849570
Entry history
Entry creation16-Apr-2014
Last entry update20-May-2021
Version number11