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Cellosaurus SLR25 (CVCL_V611)

[Text version]

Cell line name SLR25
Synonyms SLR 25
Accession CVCL_V611
Resource Identification Initiative To cite this cell line use: SLR25 (RRID:CVCL_V611)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Doubling time: 80 hours (PubMed=25984343).
Omics: shRNA library screening.
Disease Clear cell renal cell carcinoma (NCIt: C4033)
Derived from metastatic site: Not specified.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category Cancer cell line
Publications

PubMed=12907621
Tatsumi T., Herrem C.J., Olson W.C., Finke J.H., Bukowski R.M., Kinch M.S., Ranieri E., Storkus W.J.
Disease stage variation in CD4+ and CD8+ T-cell reactivity to the receptor tyrosine kinase EphA2 in patients with renal cell carcinoma.
Cancer Res. 63:4481-4489(2003)

PubMed=19470766; DOI=10.1158/0008-5472.CAN-09-0146
Beroukhim R., Brunet J.-P., Di Napoli A., Mertz K.D., Seeley A., Pires M.M., Linhart D., Worrell R.A., Moch H., Rubin M.A., Sellers W.R., Meyerson M., Linehan W.M., Kaelin W.G. Jr., Signoretti S.
Patterns of gene expression and copy-number alterations in von-Hippel Lindau disease-associated and sporadic clear cell carcinoma of the kidney.
Cancer Res. 69:4674-4681(2009)

PubMed=25984343; DOI=10.1038/sdata.2014.35
Cowley G.S., Weir B.A., Vazquez F., Tamayo P., Scott J.A., Rusin S., East-Seletsky A., Ali L.D., Gerath W.F.J., Pantel S.E., Lizotte P.H., Jiang G., Hsiao J., Tsherniak A., Dwinell E., Aoyama S., Okamoto M., Harrington W., Gelfand E., Green T.M., Tomko M.J., Gopal S., Wong T.C., Li H., Howell S., Stransky N., Liefeld T., Jang D., Bistline J., Hill Meyers B., Armstrong S.A., Anderson K.C., Stegmaier K., Reich M., Pellman D., Boehm J.S., Mesirov J.P., Golub T.R., Root D.E., Hahn W.C.
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies.
Sci. Data 1:140035-140035(2014)

PubMed=28489074; DOI=10.1038/ncomms15165
Sinha R., Winer A.G., Chevinsky M., Jakubowski C., Chen Y.-B., Dong Y., Tickoo S.K., Reuter V.E., Russo P., Coleman J.A., Sander C., Hsieh J.J., Hakimi A.A.
Analysis of renal cancer cell lines from two major resources enables genomics-guided cell line selection.
Nat. Commun. 8:15165-15165(2017)

Cross-references
Cell line databases/resources CCLE; SLR25_KIDNEY
Gene expression databases GEO; GSM374472
Other Wikidata; Q54954876
Polymorphism and mutation databases Cosmic; 2520639