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Cellosaurus EW-8 (CVCL_V618)

[Text version]

Cell line name EW-8
Synonyms EW8
Accession CVCL_V618
Resource Identification Initiative To cite this cell line use: EW-8 (RRID:CVCL_V618)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Doubling time: 30 hours (PubMed=25984343).
Omics: Deep RNAseq analysis.
Omics: shRNA library screening.
Sequence variations TP53 p.Tyr220Cys (c.659A>G) (PubMed=25010205).
Disease Ewing sarcoma (NCIt: C4817)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): PubMed=25010205

Markers:
AmelogeninX,Y
CSF1PO11
D2S133816,19
D3S135811,18
D5S81811
D7S8208,12
D8S117914,16
D13S31710
D16S53913
D18S5115
D19S43313,15.2
D21S1129,30
FGA22,23
TH019.3
TPOX8
vWA17

Run an STR similarity search on this cell line
Publications

PubMed=25010205; DOI=10.1371/journal.pgen.1004475
Brohl A.S., Solomon D.A., Chang W., Wang J., Song Y., Sindiri S., Patidar R., Hurd L., Chen L., Shern J.F., Liao H., Wen X., Gerard J., Kim J.-S., Lopez Guerrero J.A., Machado I., Wai D.H., Picci P., Triche T.J., Horvai A.E., Miettinen M., Wei J.S., Catchpoole D., Llombart-Bosch A., Waldman T., Khan J.
The genomic landscape of the Ewing sarcoma family of tumors reveals recurrent STAG2 mutation.
PLoS Genet. 10:E1004475-E1004475(2014)

PubMed=25984343; DOI=10.1038/sdata.2014.35
Cowley G.S., Weir B.A., Vazquez F., Tamayo P., Scott J.A., Rusin S., East-Seletsky A., Ali L.D., Gerath W.F.J., Pantel S.E., Lizotte P.H., Jiang G., Hsiao J., Tsherniak A., Dwinell E., Aoyama S., Okamoto M., Harrington W., Gelfand E., Green T.M., Tomko M.J., Gopal S., Wong T.C., Li H., Howell S., Stransky N., Liefeld T., Jang D., Bistline J., Hill Meyers B., Armstrong S.A., Anderson K.C., Stegmaier K., Reich M., Pellman D., Boehm J.S., Mesirov J.P., Golub T.R., Root D.E., Hahn W.C.
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies.
Sci. Data 1:140035-140035(2014)

PubMed=26351324; DOI=10.1158/1535-7163.MCT-15-0074
Teicher B.A., Polley E.C., Kunkel M., Evans D., Silvers T.E., Delosh R.M., Laudeman J., Ogle C., Reinhart R., Selby M., Connelly J., Harris E., Monks A., Morris J.
Sarcoma cell line screen of oncology drugs and investigational agents identifies patterns associated with gene and microRNA expression.
Mol. Cancer Ther. 14:2452-2462(2015)

Cross-references
Cell line databases/resources CCLE; EW8_BONE
Gene expression databases GEO; GSM1676298
GEO; GSM1701633
Other Wikidata; Q54833004
Polymorphism and mutation databases Cosmic; 2294583
Cosmic; 2228229