ID   PrEC LH
AC   CVCL_V626
SY   LH; PRECLH
DR   BioSample; SAMN10988400
DR   Cell_Model_Passport; SIDM01871
DR   DepMap; ACH-000170
DR   PharmacoDB; PrECLH_1276_2019
DR   Progenetix; CVCL_V626
DR   Wikidata; Q54948343
RX   PubMed=15604246;
RX   PubMed=30894373;
RX   PubMed=31068700;
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Population: Caucasian.
CC   Transfected with: HGNC; 11730; TERT.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Omics: Deep exome analysis.
CC   Genome ancestry: African=0.32%; Native American=0%; East Asian, North=0.26%; East Asian, South=0%; South Asian=1%; European, North=67.13%; European, South=31.28% (PubMed=30894373).
CC   Derived from site: In situ; Prostate, epithelium; UBERON=UBERON_0000428.
CC   Cell type: Epithelial cell of prostate; CL=CL_0002231.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
CA   Transformed cell line
DT   Created: 16-04-14; Last updated: 05-10-23; Version: 15
//
RX   PubMed=15604246; DOI=10.1158/0008-5472.CAN-04-2938;
RA   Berger R., Febbo P.G., Majumder P.K., Zhao J.J., Mukherjee S.,
RA   Signoretti S., Campbell K.T., Sellers W.R., Roberts T.M., Loda M.,
RA   Golub T.R., Hahn W.C.;
RT   "Androgen-induced differentiation and tumorigenicity of human prostate
RT   epithelial cells.";
RL   Cancer Res. 64:8867-8875(2004).
//
RX   PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747;
RA   Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.;
RT   "An interactive resource to probe genetic diversity and estimated
RT   ancestry in cancer cell lines.";
RL   Cancer Res. 79:1263-1273(2019).
//
RX   PubMed=31068700; DOI=10.1038/s41586-019-1186-3;
RA   Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C.,
RA   McDonald E.R. III, Barretina J.G., Gelfand E.T., Bielski C.M., Li H.-X.,
RA   Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F.,
RA   Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R.,
RA   Lu Y.-L., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C.,
RA   Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A.,
RA   Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D.,
RA   Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L.,
RA   Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A.,
RA   Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D.,
RA   Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M.,
RA   Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R.,
RA   Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A.,
RA   Sellers W.R.;
RT   "Next-generation characterization of the Cancer Cell Line
RT   Encyclopedia.";
RL   Nature 569:503-508(2019).
//