ID   CHL-2
AC   CVCL_V643
DR   ATCC; CRL-9451
DR   Wikidata; Q54812130
RX   Patent=US5017478;
CC   Group: Patented cell line.
CC   Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-9451.
CC   Sequence variation: Gene fusion; HGNC; 2352; CREM + HGNC; 3508; EWSR1; Name(s)=EWSR1-CREM (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 1787; CDKN2A; Simple; p.Trp110Ter (c.330G>A) (p.Gly125Arg, c.373G>A); Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 6877; MAPK3; Simple; p.Ile228Val (c.682A>G); Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.His193Arg (c.578A>G); ClinVar=VCV000184979; Zygosity=Homozygous (from parent cell line).
CC   Transfected with: HGNC; 9051; PLAT.
CC   Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from metastatic site: Pleural effusion.
ST   Source(s): ATCC
ST   Amelogenin: X
ST   CSF1PO: 10
ST   D13S317: 8,11
ST   D16S539: 13
ST   D5S818: 11,12
ST   D7S820: 11,13
ST   TH01: 9,9.3
ST   TPOX: 8
ST   vWA: 17
DI   NCIt; C3224; Melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens
HI   CVCL_1122 ! CHL-1
SX   Female
AG   36Y
CA   Cancer cell line
DT   Created: 16-04-14; Last updated: 23-09-21; Version: 14
//
RX   Patent=US5017478;
RA   Cashion L., Begley K., Colby W., Morser M.J.;
RT   "Transfected cells containing plasmids having genes oriented in
RT   opposing directions and methods of using.";
RL   Patent number US5017478, 21-May-1991.
//