ID   SHSY5Y-B7H6
AC   CVCL_VA24
DR   cancercelllines; CVCL_VA24
DR   Wikidata; Q54953398
RX   PubMed=29453518;
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; 427; ALK; Simple; p.Phe1174Leu (c.3522C>A); ClinVar=VCV000217852; Zygosity=Unspecified (from parent cell line).
CC   Transfected with: HGNC; 42400; NCR3LG1.
CC   Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371.
DI   NCIt; C3270; Neuroblastoma
DI   ORDO; Orphanet_635; Neuroblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0019 ! SH-SY5Y
SX   Female
AG   4Y
CA   Cancer cell line
DT   Created: 14-05-18; Last updated: 05-10-23; Version: 9
//
RX   PubMed=29453518; DOI=10.1007/s00262-018-2124-1;
RA   Gacerez A.T., Hua C.K., Ackerman M.E., Sentman C.L.;
RT   "Chimeric antigen receptors with human scFvs preferentially induce T
RT   cell anti-tumor activity against tumors with high B7H6 expression.";
RL   Cancer Immunol. Immunother. 67:749-759(2018).
//