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Cellosaurus BJAB GFP-CD20 (CVCL_VD92)

[Text version]
Cell line name BJAB GFP-CD20
Accession CVCL_VD92
Resource Identification Initiative To cite this cell line use: BJAB GFP-CD20 (RRID:CVCL_VD92)
Comments Population: African; Kenyan.
Characteristics: Expresses GFP fused to the N-terminus of MS4A1/CD20.
Virology: EBV-negative.
Transfected with: HGNC; 7315; MS4A1.
Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP).
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Groin; UBERON=UBERON_0008337.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.His193Arg (c.578A>G); ClinVar=VCV000184979; Zygosity=Unspecified (from parent cell line).
Disease Burkitt lymphoma (NCIt: C2912)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_5711 (BJAB)
Sex of cell Female
Age at sampling 5Y
Category Cancer cell line
Publications

PubMed=14976189; DOI=10.1074/jbc.M400525200
Li H.-D., Ayer L.M., Polyak M.J., Mutch C.M., Petrie R.J., Gauthier L., Shariat N., Hendzel M.J., Shaw A.R.E., Patel K.D., Deans J.P.
The CD20 calcium channel is localized to microvilli and constitutively associated with membrane rafts: antibody binding increases the affinity of the association through an epitope-dependent cross-linking-independent mechanism.
J. Biol. Chem. 279:19893-19901(2004)

PubMed=23874341; DOI=10.3389/fimmu.2013.00195
Zuccolo J., Deng L.-L., Unruh T.L., Sanyal R., Bau J.A., Storek J., Demetrick D.J., Luider J.M., Auer-Grzesiak I.A., Mansoor A., Deans J.P.
Expression of MS4A and TMEM176 genes in human B lymphocytes.
Front. Immunol. 4:195.1-195.7(2013)

Cross-references
Cell line collections (Providers) Kerafast; EUC018
Cell line databases/resources cancercelllines; CVCL_VD92
Encyclopedic resources Wikidata; Q54796978
Entry history
Entry creation14-May-2018
Last entry update05-Oct-2023
Version number9