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Cellosaurus HHUUKDi003-A (CVCL_VE83)

[Text version]

Cell line name HHUUKDi003-A
Synonyms AD-TREM2-1; AD TREM2-1
Accession CVCL_VE83
Resource Identification Initiative To cite this cell line use: HHUUKDi003-A (RRID:CVCL_VE83)
Comments From: Heinrich-Heine-Universitat Dusseldorf; Dusseldorf; Germany.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from sampling site: Peripheral blood.
Sequence variations Mutation; HGNC; 17761; TREM2; Simple; p.Arg47His (c.140G>A); ClinVar=VCV000195350; Zygosity=Heterozygous (PubMed=29602048).
Disease Alzheimer's disease 17 (NCIt: C169104)
Early-onset autosomal dominant Alzheimer disease (ORDO: Orphanet_1020)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 67Y
Category Induced pluripotent stem cell
Publications

PubMed=29602048; DOI=10.1016/j.scr.2018.03.011
Martins S., Yigit H., Bohndorf M., Graffmann N., Fiszl A.R., Wruck W., Sleegers K., Van Broeckhoven C., Adjaye J.
Lymphoblast-derived integration-free iPSC line AD-TREM2-1 from a 67 year-old Alzheimer's disease patient expressing the TREM2 p.R47H variant.
Stem Cell Res. 29:60-63(2018)

Cross-references
Cell line databases/resources hPSCreg; HHUUKDi003-A
SKIP; SKIP003218
Other Wikidata; Q54887505
Entry history
Entry creation14-May-2018
Last entry update20-May-2021
Version number7