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Cellosaurus NCI-H3122-CR1 (CVCL_VJ82)

[Text version]

Cell line name NCI-H3122-CR1
Synonyms NCI-H3122 CR1
Accession CVCL_VJ82
Resource Identification Initiative To cite this cell line use: NCI-H3122-CR1 (RRID:CVCL_VJ82)
Comments Selected for resistance to: ChEBI; CHEBI:64310; Crizotinib (Xalkori).
Sequence variations EML4-ALK gene fusion (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_5160 (NCI-H3122)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=23344087; DOI=10.1097/JTO.0b013e318283dcc0
Kim S., Kim T.M., Kim D.-W., Go H., Keam B., Lee S.-H., Ku J.-L., Chung D.H., Heo D.S.
Heterogeneity of genetic changes associated with acquired crizotinib resistance in ALK-rearranged lung cancer.
J. Thorac. Oncol. 8:415-422(2013)

Cross-references
Polymorphism and mutation databases Cosmic; 1860358
Entry history
Entry creation07-Sep-2018
Last entry updated05-Jul-2019
Version number2