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Cellosaurus NCI-H358a (CVCL_VK07)

[Text version]

Cell line name NCI-H358a
Synonyms H358a
Accession CVCL_VK07
Resource Identification Initiative To cite this cell line use: NCI-H358a (RRID:CVCL_VK07)
Sequence variations Heterozygous for KRAS p.Gly12Cys (c.34G>T) (from parent cell line).
Homozygous for TP53 deletion (from parent cell line).
Disease Minimally invasive lung adenocarcinoma (NCIt: C2923)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1559 (NCI-H358)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=8280799; DOI=10.1089/hum.1993.4.5-617
Cai D.W., Mukhopadhyay T., Liu Y., Fujiwara T., Roth J.A.
Stable expression of the wild-type p53 gene in human lung cancer cells after retrovirus-mediated gene transfer.
Hum. Gene Ther. 4:617-624(1993)

PubMed=8089864; DOI=10.1093/jnci/86.19.1458
Fujiwara T., Cai D.W., Georges R.N., Mukhopadhyay T., Grimm E.A., Roth J.A.
Therapeutic effect of a retroviral wild-type p53 expression vector in an orthotopic lung cancer model.
J. Natl. Cancer Inst. 86:1458-1462(1994)

Entry history
Entry creation07-Sep-2018
Last entry updated25-Feb-2019
Version number3