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Cellosaurus T24M (CVCL_VL60)

[Text version]

Cell line name T24M
Accession CVCL_VL60
Resource Identification Initiative To cite this cell line use: T24M (RRID:CVCL_VL60)
Comments Population: Caucasian; Swedish.
Characteristics: Established from T24 by cycles of subcutaneous injections into SCID mice.
Omics: Proteome analysis by 2D-DE/MS.
Derived from sampling site: Urinary bladder.
Sequence variations Mutation; HGNC; 5173; HRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012600; Zygosity=Homozygous (from parent cell line).
Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Mutation; HGNC; 11998; TP53; Simple; p.Tyr126Ter (c.378C>G); ClinVar=VCV000578988; Zygosity=Homozygous (from parent cell line).
Disease Bladder carcinoma (NCIt: C4912)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0554 (T24)
Sex of cell Female
Age at sampling 82Y
Category Cancer cell line
Publications

PubMed=19105184; DOI=10.1002/pmic.200800121
Makridakis M., Gagos S., Petrolekas A., Roubelakis M.G., Bitsika V., Stravodimos K., Pavlakis K., Anagnou N.P., Coleman J., Vlahou A.
Chromosomal and proteome analysis of a new T24-based cell line model for aggressive bladder cancer.
Proteomics 9:287-298(2009)

PubMed=29732388; DOI=10.3233/BLC-180167
Zuiverloon T.C.M., de Jong F.C., Costello J.C., Theodorescu D.
Systematic review: characteristics and preclinical uses of bladder cancer cell lines.
Bladder Cancer 4:169-183(2018)

Cross-references
Other Wikidata; Q98133066
Entry history
Entry creation07-Sep-2018
Last entry update20-May-2021
Version number6