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Cellosaurus HHUUKDi004-A (CVCL_VN16)

[Text version]

Cell line name HHUUKDi004-A
Synonyms AD-TREM2-3; ISRM AD TREM2-3
Accession CVCL_VN16
Resource Identification Initiative To cite this cell line use: HHUUKDi004-A (RRID:CVCL_VN16)
Comments From: Heinrich-Heine-Universitat Dusseldorf; Dusseldorf; Germany.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Sequence variations Heterozygous for TREM2 p.Arg47His (c.140G>A) (PubMed=29902745).
Disease Alzheimer's disease 17 (NCIt: C169104)
Early-onset autosomal dominant Alzheimer disease (ORDO: Orphanet_1020)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 74Y
Category Induced pluripotent stem cell

PubMed=29902745; DOI=10.1016/j.scr.2018.05.018
Martins S., Yigit H., Bohndorf M., Graffmann N., Fiszl A.R., Wruck W., Sleegers K., Van Broeckhoven C., Adjaye J.
Lymphoblast-derived integration-free iPSC line AD-TREM2-3 from a 74 year-old Alzheimer's disease patient expressing the TREM2 p.R47H variant.
Stem Cell Res. 30:141-144(2018)

Cell line databases/resources hPSCreg; HHUUKDi004-A
Entry history
Entry creation07-Sep-2018
Last entry updated12-Mar-2020
Version number3