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Cellosaurus WAe001-A-17 (CVCL_VN44)

[Text version]
Cell line name WAe001-A-17
Synonyms H1-p53(R248W/R248W); 1P6; CDMLe004-A-17
Accession CVCL_VN44
Resource Identification Initiative To cite this cell line use: WAe001-A-17 (RRID:CVCL_VN44)
Comments From: Cancer Disease Modeling Laboratory, University of Texas Health Center at Houston; Houston; USA.
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple_edited; p.Arg248Trp (c.742C>T); ClinVar=VCV000012347; Zygosity=Homozygous; Note=By TALEN (PubMed=29730572).
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_9771 (WA01)
Sex of cell Male
Age at sampling Blastocyst stage
Category Embryonic stem cell
Publications

PubMed=29730572; DOI=10.1016/j.scr.2018.04.013
Xu A., Zhou R.-J., Tu J., Huo Z.-J., Zhu D.-D., Wang D.-H., Gingold J.A., Mata H., Rao P.H., Liu M., Mohamed A.M.T., Kong C.S.L., Jewell B.E., Xia W.-Y., Zhao R.-Y., Hung M.-C., Lee D.-F.
Establishment of a human embryonic stem cell line with homozygous TP53 R248W mutant by TALEN mediated gene editing.
Stem Cell Res. 29:215-219(2018)

Cross-references
Cell line databases/resources hPSCreg; WAe001-A-17
Encyclopedic resources Wikidata; Q98134682
Entry history
Entry creation07-Sep-2018
Last entry update29-Jun-2023
Version number9