ID   WAe001-A-17
AC   CVCL_VN44
SY   H1-p53(R248W/R248W); 1P6; CDMLe004-A-17
DR   hPSCreg; WAe001-A-17
DR   Wikidata; Q98134682
RX   PubMed=29730572;
CC   From: Cancer Disease Modeling Laboratory, University of Texas Health Center at Houston; Houston; USA.
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple_edited; p.Arg248Trp (c.742C>T); ClinVar=VCV000012347; Zygosity=Homozygous; Note=By TALEN (PubMed=29730572).
CC   Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
CC   Cell type: Embryonic stem cell; CL=CL_0002322.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_9771 ! WA01
SX   Male
AG   Blastocyst stage
CA   Embryonic stem cell
DT   Created: 07-09-18; Last updated: 29-06-23; Version: 9
//
RX   PubMed=29730572; DOI=10.1016/j.scr.2018.04.013;
RA   Xu A., Zhou R.-J., Tu J., Huo Z.-J., Zhu D.-D., Wang D.-H.,
RA   Gingold J.A., Mata H., Rao P.H., Liu M., Mohamed A.M.T., Kong C.S.L.,
RA   Jewell B.E., Xia W.-Y., Zhao R.-Y., Hung M.-C., Lee D.-F.;
RT   "Establishment of a human embryonic stem cell line with homozygous
RT   TP53 R248W mutant by TALEN mediated gene editing.";
RL   Stem Cell Res. 29:215-219(2018).
//