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Cellosaurus AGS NOD1 KO clone 41A8 (CVCL_VP28)

[Text version]

Cell line name AGS NOD1 KO clone 41A8
Synonyms AGS NOD1 KO (Clone 41A8); NOD1 KO clone#1
Accession CVCL_VP28
Resource Identification Initiative To cite this cell line use: AGS NOD1 KO clone 41A8 (RRID:CVCL_VP28)
Comments Knockout cell: Method=CRISPR/Cas9; HGNC; 16390; NOD1.
Sequence variations Heterozygous for CTNNB1 p.Gly34Glu (c.101G>A) (from parent cell line).
Heterozygous for KRAS p.Gly12Asp (c.35G>A) (ClinVar=VCV000012582) (from parent cell line).
Heterozygous for PIK3CA p.Glu453Lys (c.1357G>A) (ClinVar=VCV000376470) and p.Glu545Ala (c.1634A>C) (from parent cell line).
Disease Gastric adenocarcinoma (NCIt: C4004)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0139 (AGS)
Sex of cell Female
Age at sampling 54Y
Category Cancer cell line

PubMed=29392836; DOI=10.1111/cmi.12826
Tran L.S., Tran D., De Paoli A., D'Costa K., Creed S.J., Ng G.Z., Le L., Sutton P., Silke J., Nachbur U., Ferrero R.L.
NOD1 is required for Helicobacter pylori induction of IL-33 responses in gastric epithelial cells.
Cell. Microbiol. 20:E12826-E12826(2018)

Cell line collections Ximbio; 153733
Other Wikidata; Q93323548
Entry history
Entry creation07-Sep-2018
Last entry update02-Jul-2020
Version number3