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Cellosaurus AGS NOD1 KO clone 41A8 (CVCL_VP28)

[Text version]

Cell line name AGS NOD1 KO clone 41A8
Synonyms AGS NOD1 KO (Clone 41A8); NOD1 KO clone#1
Accession CVCL_VP28
Resource Identification Initiative To cite this cell line use: AGS NOD1 KO clone 41A8 (RRID:CVCL_VP28)
Comments Population: Caucasian.
Knockout cell: Method=CRISPR/Cas9; HGNC; 16390; NOD1.
Derived from sampling site: Stomach.
Sequence variations Mutation; HGNC; 2514; CTNNB1; Simple; p.Gly34Glu (c.101G>A); ClinVar=VCV000017584; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu453Lys (c.1357G>A); ClinVar=VCV000376470; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu545Ala (c.1634A>C); ClinVar=VCV000013659; Zygosity=Heterozygous (from parent cell line).
Disease Gastric adenocarcinoma (NCIt: C4004)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0139 (AGS)
Sex of cell Female
Age at sampling 54Y
Category Cancer cell line
Publications

PubMed=29392836; DOI=10.1111/cmi.12826
Tran L.S., Tran D., De Paoli A., D'Costa K., Creed S.J., Ng G.Z., Le L., Sutton P., Silke J., Nachbur U., Ferrero R.L.
NOD1 is required for Helicobacter pylori induction of IL-33 responses in gastric epithelial cells.
Cell. Microbiol. 20:E12826-E12826(2018)

Cross-references
Cell line collections Ximbio; 153733
Other Wikidata; Q93323548
Entry history
Entry creation07-Sep-2018
Last entry update20-May-2021
Version number6