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Cellosaurus AGS NOD1 KO clone 41H8 (CVCL_VP29)

[Text version]
Cell line name AGS NOD1 KO clone 41H8
Synonyms AGS NOD1 KO (Clone 41H8); NOD1 KO clone#2
Accession CVCL_VP29
Resource Identification Initiative To cite this cell line use: AGS NOD1 KO clone 41H8 (RRID:CVCL_VP29)
Comments Population: Caucasian.
Knockout cell: Method=CRISPR/Cas9; HGNC; 16390; NOD1.
Derived from site: In situ; Stomach; UBERON=UBERON_0000945.
Sequence variations
  • Mutation; HGNC; 2514; CTNNB1; Simple; p.Gly34Glu (c.101G>A); ClinVar=VCV000017584; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu453Lys (c.1357G>A); ClinVar=VCV000376470; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu545Ala (c.1634A>C); ClinVar=VCV000013659; Zygosity=Heterozygous (from parent cell line).
Disease Gastric adenocarcinoma (NCIt: C4004)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0139 (AGS)
Sex of cell Female
Age at sampling 54Y
Category Cancer cell line
Publications

PubMed=29392836; DOI=10.1111/cmi.12826
Tran L.S., Tran D., De Paoli A., D'Costa K., Creed S.J., Ng G.Z., Le L., Sutton P., Silke J., Nachbur U., Ferrero R.L.
NOD1 is required for Helicobacter pylori induction of IL-33 responses in gastric epithelial cells.
Cell. Microbiol. 20:e12826.1-e12826.12(2018)

Cross-references
Cell line collections (Providers) CancerTools; 153734
Ximbio; 153734
Cell line databases/resources cancercelllines; CVCL_VP29
Encyclopedic resources Wikidata; Q93323549
Entry history
Entry creation07-Sep-2018
Last entry update05-Oct-2023
Version number10