ID   FaDu(DD)
AC   CVCL_VP44
SY   FaDuDD; FADUDD; FaDudd; FaDu DD; FADU DD
DR   cancercelllines; CVCL_VP44
DR   GEO; GSM1716417
DR   GEO; GSM1716418
DR   GEO; GSM1716419
DR   GEO; GSM1716420
DR   GEO; GSM1716421
DR   GEO; GSM1716422
DR   GEO; GSM1716427
DR   GEO; GSM1716428
DR   GEO; GSM1716429
DR   GEO; GSM1716430
DR   Wikidata; Q93549515
RX   PubMed=11799138;
RX   PubMed=20429727;
CC   Population: Indian.
CC   Sequence variation: Mutation; HGNC; 1787; CDKN2A; Simple; c.151-1G>T; ClinVar=VCV000422058; Zygosity=Homozygous; Note=Splice acceptor mutation (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 3595; FAT1; Simple; p.Lys3277Asnfs*4 (c.9828delG) (p.Gly3276fs); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; c.376-1G>A (p.Tyr126_Lys132del, c.376_396del21); ClinVar=VCV000481003; Zygosity=Hemizygous; Note=Splice acceptor mutation (PubMed=11799138).
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: In situ; Pharynx, hypopharynx; UBERON=UBERON_0001051.
DI   NCIt; C4043; Hypopharyngeal squamous cell carcinoma
DI   ORDO; Orphanet_494547; Squamous cell carcinoma of the hypopharynx
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1218 ! FaDu
SX   Male
AG   56Y
CA   Cancer cell line
DT   Created: 07-09-18; Last updated: 05-10-23; Version: 11
//
RX   PubMed=11799138; DOI=10.1177/002215540205000207;
RA   Eicheler W., Zips D., Dorfler A., Grenman R., Baumann M.;
RT   "Splicing mutations in TP53 in human squamous cell carcinoma lines
RT   influence immunohistochemical detection.";
RL   J. Histochem. Cytochem. 50:197-204(2002).
//
RX   PubMed=20429727; DOI=10.3109/02841861003614343;
RA   Sorensen B.S., Toustrup K., Horsman M.R., Overgaard J., Alsner J.;
RT   "Identifying pH independent hypoxia induced genes in human squamous
RT   cell carcinomas in vitro.";
RL   Acta Oncol. 49:895-905(2010).
//