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Cellosaurus UOWi006-A (CVCL_VP84)

[Text version]
Cell line name UOWi006-A
Synonyms RB7-11; SAD1
Accession CVCL_VP84
Resource Identification Initiative To cite this cell line use: UOWi006-A (RRID:CVCL_VP84)
Comments From: University of Wollongong; Wollongong; Australia.
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
  • Mutation; HGNC; 613; APOE; Simple; p.Cys130Arg (c.388T>C); ClinVar=VCV000017864; Zygosity=Homozygous; Note=ApoE4 allele (PubMed=32887382).
Disease Alzheimer's disease (NCIt: C2866)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 83Y
Category Induced pluripotent stem cell
Publications

PubMed=32887382; DOI=10.3390/cells9092018
Munoz S.S., Engel M., Balez R., Do-Ha D., Cabral-da-Silva M.C., Hernandez D., Berg T., Fifita J.A., Grima N., Yang S., Blair I.P., Nicholson G., Cook A.L., Hewitt A.W., Pebay A., Ooi L.
A simple differentiation protocol for generation of induced pluripotent stem cell-derived basal forebrain-like cholinergic neurons for Alzheimer's disease and frontotemporal dementia disease modeling.
Cells 9:2018.1-2018.17(2020)

Cross-references
Cell line databases/resources hPSCreg; UOWi006-A
Encyclopedic resources Wikidata; Q98134328
Entry history
Entry creation07-Sep-2018
Last entry update29-Jun-2023
Version number5