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Cellosaurus SCL215 (CVCL_VQ64)

[Text version]

Cell line name SCL215
Accession CVCL_VQ64
Resource Identification Initiative To cite this cell line use: SCL215 (RRID:CVCL_VQ64)
Comments Characteristics: Expresses a rat GNRHR fused to a catfish GNRHR C-terminal cytoplasmic domain. The fusion protein binds GNRH and analogs but this does not activate signaling.
Transfected with: RGD; 70513; Gnrhr.
Transfected with: UniProtKB; O42329; Clarias gariepinus cfGnRH-R (with p.Met1_Phe328del).
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0045 (HEK293)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Publications

CLPUB00443
Meyer C.
Characterisation of the direct antiproliferative effects of a gonadotrophin-releasing hormone analogue.
Thesis PhD (2012), University of Edinburgh, United Kingdom

PubMed=23202794; DOI=10.1530/ERC-12-0192
Meyer C., Sims A.H., Morgan K., Harrison B., Muir M., Bai J., Faratian D., Millar R.P., Langdon S.P.
Transcript and protein profiling identifies signaling, growth arrest, apoptosis, and NF-kappaB survival signatures following GNRH receptor activation.
Endocr. Relat. Cancer 20:123-136(2013)

Entry history
Entry creation13-Nov-2018
Last entry update13-Nov-2018
Version number1