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Cellosaurus SCL60 (CVCL_VQ89)

[Text version]

Cell line name SCL60
Synonyms HEK293[SCL60]; 293-A2
Accession CVCL_VQ89
Resource Identification Initiative To cite this cell line use: SCL60 (RRID:CVCL_VQ89)
Comments Doubling time: 21.4 hours (PubMed=18676858).
Transfected with: RGD; 70513; Gnrhr.
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0045 (HEK293)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line

PubMed=7588262; DOI=10.1210/endo.136.11.7588262
Anderson L., McGregor A., Cook J.V., Chilvers E., Eidne K.A.
Rapid desensitization of GnRH-stimulated intracellular signalling events in alpha T3-1 and HEK-293 cells expressing the GnRH receptor.
Endocrinology 136:5228-5231(1995)

PubMed=18676858; DOI=10.1158/0008-5472.CAN-08-0197
Morgan K., Stewart A.J., Miller N., Mullen P., Muir M., Dodds M., Medda F., Harrison D., Langdon S.P., Millar R.P.
Gonadotropin-releasing hormone receptor levels and cell context affect tumor cell responses to agonist in vitro and in vivo.
Cancer Res. 68:6331-6340(2008)

Meyer C.
Characterisation of the direct antiproliferative effects of a gonadotrophin-releasing hormone analogue.
Thesis PhD (2012), University of Edinburgh, United Kingdom

PubMed=23202794; DOI=10.1530/ERC-12-0192
Meyer C., Sims A.H., Morgan K., Harrison B., Muir M., Bai J., Faratian D., Millar R.P., Langdon S.P.
Transcript and protein profiling identifies signaling, growth arrest, apoptosis, and NF-kappaB survival signatures following GNRH receptor activation.
Endocr. Relat. Cancer 20:123-136(2013)

Entry history
Entry creation13-Nov-2018
Last entry update13-Nov-2018
Version number1