ID   SCL60
AC   CVCL_VQ89
SY   HEK293[SCL60]; 293-A2
DR   Wikidata; Q98129413
RX   CelloPub=CLPUB00443;
RX   PubMed=7588262;
RX   PubMed=18676858;
RX   PubMed=23202794;
CC   Doubling time: 21.4 hours (PubMed=18676858).
CC   Transfected with: RGD; 70513; Gnrhr.
CC   Transformant: NCBI_TaxID; 28285; Adenovirus 5.
CC   Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0045 ! HEK293
SX   Female
AG   Fetus
CA   Transformed cell line
DT   Created: 13-11-18; Last updated: 29-06-23; Version: 4
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RX   CelloPub=CLPUB00443;
RA   Meyer C.;
RT   "Characterisation of the direct antiproliferative effects of a
RT   gonadotrophin-releasing hormone analogue.";
RL   Thesis PhD (2012), University of Edinburgh, United Kingdom.
//
RX   PubMed=7588262; DOI=10.1210/endo.136.11.7588262;
RA   Anderson L., McGregor A., Cook J.V., Chilvers E., Eidne K.A.;
RT   "Rapid desensitization of GnRH-stimulated intracellular signalling
RT   events in alpha T3-1 and HEK-293 cells expressing the GnRH receptor.";
RL   Endocrinology 136:5228-5231(1995).
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RX   PubMed=18676858; DOI=10.1158/0008-5472.CAN-08-0197;
RA   Morgan K., Stewart A.J., Miller N., Mullen P., Muir M., Dodds M.,
RA   Medda F., Harrison D., Langdon S.P., Millar R.P.;
RT   "Gonadotropin-releasing hormone receptor levels and cell context
RT   affect tumor cell responses to agonist in vitro and in vivo.";
RL   Cancer Res. 68:6331-6340(2008).
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RX   PubMed=23202794; DOI=10.1530/ERC-12-0192;
RA   Meyer C., Sims A.H., Morgan K., Harrison B., Muir M., Bai J.-N.,
RA   Faratian D., Millar R.P., Langdon S.P.;
RT   "Transcript and protein profiling identifies signaling, growth arrest,
RT   apoptosis, and NF-kappaB survival signatures following GNRH receptor
RT   activation.";
RL   Endocr. Relat. Cancer 20:123-136(2013).
//