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Cellosaurus 786-M1A (CVCL_VR30)

[Text version]

Cell line name 786-M1A
Accession CVCL_VR30
Resource Identification Initiative To cite this cell line use: 786-M1A (RRID:CVCL_VR30)
Comments Characteristics: Established from lung metastatis in NOD/SCID mice which were intravenous inoculated with the parental cell line.
Miscellaneous: STR profile from MSKCC antibody and bioresource core facility.
Sequence variations Homozygous for PTEN p.Gln149Ter (c.445C>T) (from parent cell line).
Homozygous for VHL p.Gly104fs*55 (c.311delG) (from parent cell line).
Disease Renal cell carcinoma (NCIt: C9385)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1051 (786-O)
Children:
CVCL_VR32 (786-M2A)CVCL_VR33 (786-M2B)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
STR profile Source(s): MSKCC

Markers:
AmelogeninX,Y
CSF1PO10
D2S133817,18
D3S135816
D5S8189
D7S82011,12
D8S117913
D13S3178
D16S53912
D18S5113,14
D19S43314,15
D21S1129,30
FGA24
TH016,9.3
TPOX8,11
vWA15,17

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Publications

PubMed=23223005; DOI=10.1038/nm.3029
Vanharanta S., Shu W., Brenet F., Hakimi A.A., Heguy A., Viale A., Reuter V.E., Hsieh J.J.-D., Scandura J.M., Massague J.
Epigenetic expansion of VHL-HIF signal output drives multiorgan metastasis in renal cancer.
Nat. Med. 19:50-56(2013)

Cross-references
Gene expression databases GEO; GSM800328
Other Wikidata; Q93309878
Entry history
Entry creation13-Nov-2018
Last entry update02-Jul-2020
Version number2