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Cellosaurus 786-TGL (CVCL_VR34)

[Text version]

Cell line name 786-TGL
Synonyms 786-HSV1-TK/GFP/Fluc
Accession CVCL_VR34
Resource Identification Initiative To cite this cell line use: 786-TGL (RRID:CVCL_VR34)
Comments Characteristics: Transfected with HSV1-TK/GFP/Fluc (TGL).
Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP).
Transfected with: UniProtKB; P08659; Firefly luciferase.
Transfected with: UniProtKB; Q9QNF7; Human herpesvirus 1 TK.
Miscellaneous: STR profile from MSKCC antibody and bioresource core facility.
Sequence variations Homozygous for PTEN p.Gln149Ter (c.445C>T) (from parent cell line).
TERT c.228C>T (-124C>T); in promoter (from parent cell line).
Heterozygous for TP53 c.560-2A>G; splice acceptor mutation and p.Pro278Ala (c.832C>G) (ClinVar=VCV000376645) (from parent cell line).
Homozygous for VHL p.Gly104fs*55 (c.311delG) (from parent cell line).
Disease Renal cell carcinoma (NCIt: C9385)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1051 (786-O)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
STR profile Source(s): MSKCC

Markers:
AmelogeninX,Y
CSF1PO10
D2S133817,18
D3S135816
D5S8189
D7S82011,12
D8S117913
D13S3178
D16S53912
D18S5113,14
D19S43314,15
D21S1129,30
FGA24
TH016,9.3
TPOX8,11
vWA15,17

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Cross-references
Other Wikidata; Q93309884
Entry history
Entry creation13-Nov-2018
Last entry update02-Jul-2020
Version number4