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Cellosaurus MDA231-BrM2-831 (CVCL_VR36)

[Text version]

Cell line name MDA231-BrM2-831
Synonyms MDA 231 BrM2 831; MDA-MB-231-BrM2 831
Accession CVCL_VR36
Resource Identification Initiative To cite this cell line use: MDA231-BrM2-831 (RRID:CVCL_VR36)
Comments Group: Triple negative breast cancer (TNBC) cell line.
Characteristics: Established from MDA231-TGL cell line after 2 passage in nude mice.
Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP).
Transfected with: UniProtKB; P08659; Firefly luciferase.
Transfected with: UniProtKB; Q9QNF7; Human herpesvirus 1 TK.
Miscellaneous: STR profile from MSKCC antibody and bioresource core facility.
Sequence variations Heterozygous for BRAF p.Gly464Val (c.1391G>T) (from parent cell line).
Homozygous for CDKN2A deletion (from parent cell line).
Heterozygous for KRAS p.Gly13Asp (c.38G>A) (from parent cell line).
TERT c.228C>T (-124C>T); in promoter (from parent cell line).
Homozygous for TP53 p.Arg280Lys (c.839G>A) (from parent cell line).
Disease Breast adenocarcinoma (NCIt: C5214)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_VR35 (MDA231-TGL)
Sex of cell Female
Age at sampling 51Y
Category Cancer cell line
STR profile Source(s): MSKCC

Markers:
AmelogeninX
CSF1PO12,13
D1S165615,17
D2S44114,15
D2S133820,21
D3S135816
D5S81812
D7S8208
D8S117913
D10S124814,16
D12S39117
D13S31713
D16S53912
D18S5111,16
D19S43311
D21S1133.2
D22S104516
FGA22,23
Penta D14
Penta E11
TH017,9.3
TPOX8,9
vWA15

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Publications

PubMed=19421193; DOI=10.1038/nature08021
Bos P.D., Zhang X.H.-F., Nadal C., Shu W., Gomis R.R., Nguyen D.X., Minn A.J., van de Vijver M.J., Gerald W.L., Foekens J.A., Massague J.
Genes that mediate breast cancer metastasis to the brain.
Nature 459:1005-1009(2009)

Entry history
Entry creation13-Nov-2018
Last entry updated05-Jul-2019
Version number3