ID   CHO-K1 MMC-2
AC   CVCL_VU06
SY   MMC-2; CHO-MMC-2
DR   Wikidata; Q93451806
RX   PubMed=2110815;
RX   PubMed=2413991;
RX   PubMed=3093856;
RX   PubMed=16143348;
CC   Characteristics: Sensitive to mitomycin C.
CC   Sequence variation: Mutation; UniProtKB; A0MQ57; Ercc3; Simple; p.Gln739Ter (c.2215C>T); Zygosity=Unspecified (PubMed=16143348).
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
CC   Cell type: Epithelial cell of ovary; CL=CL_2000064.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_0214 ! CHO-K1
SX   Female
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 24-05-19; Last updated: 30-01-24; Version: 7
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RX   PubMed=2110815; DOI=10.1038/bjc.1990.162;
RA   Keohane A., Godden J., Stratford I.J., Adams G.E.;
RT   "The effects of three bioreductive drugs (mitomycin C, RSU-1069 and
RT   SR4233) on cell lines selected for their sensitivity to mitomycin C or
RT   ionising radiation.";
RL   Br. J. Cancer 61:722-726(1990).
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RX   PubMed=2413991;
RA   Robson C.N., Harris A.L., Hickson I.D.;
RT   "Isolation and characterization of Chinese hamster ovary cell lines
RT   sensitive to mitomycin C and bleomycin.";
RL   Cancer Res. 45:5304-5309(1985).
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RX   PubMed=3093856; DOI=10.1016/0027-5107(86)90049-7;
RA   Robson C.N., Hickson I.D.;
RT   "Genetic analysis of mitomycin-C-sensitive mutants of a Chinese
RT   hamster ovary cell line.";
RL   Mutat. Res. 163:201-208(1986).
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RX   PubMed=16143348; DOI=10.1016/j.mrfmmm.2005.07.013;
RA   Hall H., Gursky J., Nicodemou A., Rybanska I., Kimlickova E.,
RA   Pirsel M.;
RT   "Characterization of ERCC3 mutations in the Chinese hamster ovary
RT   27-1, UV24 and MMC-2 cell lines.";
RL   Mutat. Res. 593:177-186(2006).
//