ID   MHCC97-H Scrm shRNA
AC   CVCL_VU24
SY   MHCC97-H scrambled shRNA; MHCC97-H shRNA control
DR   cancercelllines; CVCL_VU24
DR   GEO; GSM940340
DR   GEO; GSM940341
DR   GEO; GSM940342
DR   Wikidata; Q95989436
RX   PubMed=25886575;
RX   PubMed=26000702;
CC   Population: Chinese.
CC   Characteristics: Transfected with a scrambled shRNA, control cell line for MHCC97-H CD44s shRNA (Cellosaurus=CVCL_VU23) and MHCC97-H c-Met shRNA (Cellosaurus=CVCL_VU22).
CC   Sequence variation: Mutation; HGNC; 14310; BRD7; Simple; p.Glu277Glyfs*18 (c.830_831delAG); Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 23177; KEAP1; Simple; p.Pro445Glnfs*13 (c.1334delC); Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Glu51Ter (c.151G>T); ClinVar=VCV000568781; Zygosity=Unspecified (from parent cell line).
CC   Transformant: NCBI_TaxID; 10407; Hepatitis B virus (HBV).
CC   Omics: Transcriptome analysis by microarray.
DI   NCIt; C7956; Adult hepatocellular carcinoma
DI   ORDO; Orphanet_210159; Adult hepatocellular carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_4972 ! MHCC97-H
SX   Male
AG   39Y
CA   Cancer cell line
DT   Created: 24-05-19; Last updated: 05-10-23; Version: 7
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RX   PubMed=25886575; DOI=10.1186/s12885-015-1166-4;
RA   Dang H., Steinway S.N., Ding W., Rountree C.B.;
RT   "Induction of tumor initiation is dependent on CD44s in c-Met(+)
RT   hepatocellular carcinoma.";
RL   BMC Cancer 15:161.1-161.11(2015).
//
RX   PubMed=26000702; DOI=10.1371/journal.pone.0128159;
RA   Steinway S.N., Dang H., You H., Rountree C.B., Ding W.;
RT   "The EGFR/ERBB3 pathway acts as a compensatory survival mechanism upon
RT   c-Met inhibition in human c-Met+ hepatocellular carcinoma.";
RL   PLoS ONE 10:E0128159-E0128159(2015).
//