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Cellosaurus KM12-L4A (CVCL_W220)

[Text version]

Cell line name KM12-L4A
Synonyms Km 12 L4A; KM12L4-A; KM12L4A; KM12L4a
Accession CVCL_W220
Resource Identification Initiative To cite this cell line use: KM12-L4A (RRID:CVCL_W220)
Comments Registration: Chiron Master Culture Collection; CMCC 11606 (CMCC #11606).
Sequence variations Homozygous for ACVR2A p.Lys437fs*5 (c.1310delA) (from parent cell line).
Heterozygous for APC p.Asn1819fs*7 (c.5454_5455insA) (from parent cell line).
Heterozygous for BRCA2 p.Asn1784Hisfs*7 (c.5350_5351delAA) (from parent cell line).
Heterozygous for PTEN p.Gly129Ter (c.385G>T) and p.Lys267fs*9 (c.800delA) (from parent cell line).
Heterozygous for TGFBR2 p.Lys128Serfs*35 (c.383delA) (from parent cell line).
Heterozygous for TP53 p.Arg72fs*51 (c.215delG) (from parent cell line).
Disease Colon carcinoma (NCIt: C4910)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_5946 (KM12-L4)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=3349467
Morikawa K., Walker S.M., Jessup J.M., Fidler I.J.
In vivo selection of highly metastatic cells from surgical specimens of different primary human colon carcinomas implanted into nude mice.
Cancer Res. 48:1943-1948(1988)

Cross-references
Cell line collections ATCC; CRL-12496 - Discontinued
Other Wikidata; Q54900058