Cellosaurus KY-MTX (CVCL_W293)

Cell line name KY-MTX
Synonyms KY821/MTX
Accession CVCL_W293
Resource Identification Initiative To cite this cell line use: KY-MTX (RRID:CVCL_W293)
Comments Selected for resistance to: ChEBI; CHEBI:44185; Methotrexate (MTX).
Derived from sampling site: Meninges.
Disease Acute myelomonocytic leukemia (NCIt: C7463)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1346 (KY821)
Sex of cell Male
Age at sampling 28Y
Category Cancer cell line
Publications

PubMed=1560671; DOI=10.1016/0145-2126(92)90059-G
Saito H., Kishi K., Narita M., Furukawa T., Nagura E., Maekawa T., Abe T., Shibata A.
A new myeloblastic leukemia cell line with double minute chromosomes Induction of methotrexate resistance and dihydrofolate reductase gene amplification.
Leuk. Res. 16:217-226(1992)

PubMed=8387619; DOI=10.1016/0145-2126(93)90019-H
Fukuda T., Kakihara T., Kamishima T., Ohnishi Y., Naito M., Kishi K., Shibata A.
Different effects of various hematopoietic growth factors on myelomonocytic cell line (KY-821) and its drug-resistant sublines.
Leuk. Res. 17:325-332(1993)