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Cellosaurus MCF-7aro Let-R (CVCL_W348)

[Text version]

Cell line name MCF-7aro Let-R
Synonyms MCF-7aro/LetR; MCF-7-AroR-Let-R; MCF7aroLetR; Let-R
Accession CVCL_W348
Resource Identification Initiative To cite this cell line use: MCF-7aro Let-R (RRID:CVCL_W348)
Comments Selected for resistance to: ChEBI; CHEBI:6413; Letrozole.
Transfected with: HGNC; 2594; CYP19A1.
Sequence variations Homozygous for CDKN2A deletion (from parent cell line).
Heterozygous for PIK3CA p.Glu545Lys (c.1633G>A) (from parent cell line).
Disease Invasive ductal carcinoma, not otherwise specified (NCIt: C4194)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_9580 (MCF-7aro)
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line
Web pages http://www.rcsismj.com/wp-content/uploads/RCSIsmj-Vol5-Aromatase-Inhibitor-Resistant-Breast-Ca.pdf
Publications

DOI=10.1186/1753-6561-6-S4-P3
Harris E., Vareslija D., O'Hara J., Hill A., Young L.
Characterising an aromatase inhibitor resistant breast cancer cell line.
BMC Proc. 6 Suppl. 4:P3-P3(2012)

Cross-references
Cell line collections Ximbio; 151781
Other Wikidata; Q54904401
Entry history
Entry creation16-Apr-2014
Last entry updated25-Feb-2019
Version number11